ChemBioPlants Network

ChemBioPlants Network University of Oxford

Emily Flashman

http://flashman.chem.ox.ac.uk/
Emily.flashman@chem.ox.ac.uk

The research in my lab aims to understand the molecular mechanisms of oxygen sensing in both animals and plants. All aerobic organisms must balance oxygen supply and demand, and therefore need response systems when oxygen availability drops (hypoxia) to allow adaptation to hypoxic conditions. We are investigating a number of oxygen sensing systems including HIF hydroxylases and histone lysine demethylases in animals and the Plant Cysteine Oxidases (PCOs) that are involved in oxygen sensing in plants.

We are currently collaborating with Lee Sweetlove (Department of Plant Sciences) to investigate whether the PCO pathway is involved in a post-harvest disease of potato tubers.